Peer-reviewed publications are listed below by year with PDFs for download and DOI links. You can also find our publications on Google Scholar and Pubmed.

Magnetically powered chitosan milliwheels for rapid translation, barrier function rescue, and delivery of therapeutic proteins to the inflamed gut epithelium. bioRxiv  

Low normal factor V enhanced thrombin generation in hemophilia A through a substrate competition mechanism with factor Xa. bioRxiv  

Zoster-associated prothrombotic plasma exosomes and increased stroke risk Journal of Infectious Diseases,   in press.

Apolipoprotein A-1, elevated in trauma patients, inhibits platelet activation and decreases clot strength.  Platelets,   33:1119-1131.

Nanomedicine platform for targeting activated neutrophils and neutrophil-platelet complexes using an α1-antitrypsin-derived peptide. Nature Nanotechnology   17:1004-1014

Multimodal microwheel swarms for targeting in three-dimensional networks. Scientific Reports   12:5078 PDF

Delivery and actuation of aerosolized microbots. Nano Select   3:1185-1191. PDF

Isotopically Nonstationary 13C Metabolic Flux Analysis in Resting and Activated Human Platelets. Metabolic Engineering,   22, 2022:313-322.

Breaking the fibrinolytic speed limit with microwheel co-delivery of tissue plasminogen activator and plasminogen. Journal of Thrombosis and Haemostasis,   20: 486-497.

Guidance on the critical shortage of sodium citrate coagulation tubes for hemostasis testing. Journal of Thrombosis and Haemostasis,   19(2021):2857-2861. PDF

An “arterial thrombosis-on-a-chip” microfluidic device for investigating the effect of anti-thrombotic drugs. Lab on a Chip,   21 (2021), 4104-4117. PDF

Physical forces regulating hemostasis and thrombosis: vessels, cells, and molecules in illustrated review. Research and Practice in Thrombosis and Haemostasis,   5 (2021):e12548 PDF

A tail of two ITAMs: GPVI/FcRγ and FcγRIIa’s role in platelet activation and thrombus stability. Research and Practice in Thrombosis and Haemostasis,   5 (2021):e12564. PDF

Platelet activation contributes to hypoxia-induced inflammation. American Journal of Physiology - Lung Cellular and Molecular Physiology,   320:L413-L421

In vitro flow-based assay: from simple towards more sophisticated models for mimicking hemostasis and thrombosis. Journal of Thrombosis and Haemostasis,   19:582-587.

Computationally driven discovery in coagulation. Arteriosclerosis, Thrombosis, and Vascular Biology,   41:79-86 PDF

The art and science of building a computational model to understand hemostasis. Seminars on Thrombosis and Hemostasis,   47:129-138 PDF

Transport of colloidal particles in microscopic porous media analogs with surface charge heterogeneity: experiments and fundamental role of single-bead deposition. Environmental Science & Technology,   54:13651-13660

New insights into platelet dysfunction in Kawasaki Disease using a microfluidic model of thrombosis. The Journal of Pediatrics,   226: 10-11.

Illustrated State‐of‐the‐Art Capsules of the ISTH 2020 Congress. Research and Practice in Thrombosis and Haemostasis,   4: 680-713. PDF

An experimental design for the control and assembly of magnetic microwheels. Review of Scientific Instruments,   91: 093701.

A mathematical model of platelet aggregation in an extravascular injury under flow Multiscale Modeling and Simulation,   18:1489-1524.

Pathologic shear and elongation rates do not cause cleavage of von Willebrand factor by ADAMTS13 in a purified system. Cellular and Molecular Bioengineering, in press.   13: 379-390

Platelet activation in experimental murine neonatal pulmonary hypertension. Physiological Reports,   8: e14386. PDF

Adsorption and absorption of collagen peptides to polydimethylsiloxane and its influence on platelet adhesion flow assays. Micromachines,   11: 62 PDF

A mathematical model of coagulation under flow identifies factor V as a modifier of thrombin generation in hemophilia A. Journal of Thrombosis and Haemostasis,   18: 306-317.

Scaling law for slip flow of gases in nanoporous media from nanofluidics, rock, and pore-scale simulations Fuel,   236: 1065-1077

Engineered micro- and nanoparticles for fibrinolysis. Journal of Thrombosis and Haemostasis,   17: 2004-2015.

Tranexamic acid for trauma: repackaged and redelivered. Journal of Thrombosis and Haemostasis,   17: 1626-1628.

Turbulent flow promotes cleavage of von Willebrand factor by ADAMTS13. Arteriosclerosis, Thrombosis, and Vascular Biology,   39: 1831-1842. PDF

Microwheels on microroads: Enhanced translation on topographical surfaces. Science Robotics,   4: eaaw9525.

AC/DC magnetic fields for enhanced translation of colloidal microwheels. Langmuir,   35 (2019):3455-3460.

A local and global sensitivity analysis of a mathematical model of coagulation and platelet deposition under flow. PLoS One,   13: e0200917.

Effect of chemical and physical heterogeneities on colloid-facilitated cesium transport. Journal of Contaminant Hydrology,   213:22-27.

Platelets drive thrombus growth in a hematocrit and glycoprotein VI dependent manner in an in vitro model of venous thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology,   38: 1052-1062. PDF

The small molecule MERTK inhibitor UNC2025 decreases platelet activation and prevents thrombosis. Journal of Thrombosis and Haemostasis,   16: 352-363. PDF

Evaluation of a microfluidic flow assay to screen for von Willebrand disease and low von Willebrand factor levels. Journal of Thrombosis and Haemostasis,   16: 104-115. PDF

Enhanced fibrinolysis with magnetically powered colloidal microwheels. Small,   13: 1700954. PDF

Temperature effects on the activity, shape, and storage of platelets from 13-lined ground squirrels. Journal of Comparative Physiology B,   187: 815-825. PDF

Flow chamber and microfluidic approaches for measuring thrombus formation in genetic bleeding disorders. Platelets,   28: 463-471. PDF

Magnetic microlassos for reversible cargo capture, transport, and release. Langmuir,   33: 5932-5937.

Elevated hematocrit enhances platelet accumulation following vascular injury. Blood,   129: 2537-2546 PDF

Apoptosis signal-regulating kinase 1 regulates platelet granule secretion, thromboxane A2 generation, and thrombus formation in mice. Blood,   129: 1197-1209. PDF

A microfluidic model of hemostasis sensitive to platelet function and coagulation. Cellular and Molecular Bioengineering,   10: 3-15 PDF

Effect of pore-size distribution on phase transition of hydrocarbon mixtures in nanoporous media. SPE Journal,   21: 1981-1995.

Non reciprocal skewed rolling of a colloidal wheel due to induced chirality. Soft Matter,   12: 9314-9320.

Bead-based microfluidic sediment analogs: Fabrication and colloid transport. Langmuir,   32: 9342-9350.

Blood flow and mass transfer regulation of coagulation. Blood Reviews,   30: 357-368. PDF

High-throughput linear optical stretcher for mechanical characterization of blood cells. Cytometry: Part A,   32: 9342-9350. PDF

Dimensional analysis and scaling relevant to flow models of thrombus formation. Journal of Thrombosis and Haemostasis,   14: 619-622. PDF

Surface-enabled propulsion and control of colloidal microwheels. Nature Communication,   7: 10225. PDF

In microfluidico: Recreating in vivo hemodynamics using miniaturized devices. Biorheology,   52: 303-318. PDF

On-chip recalcification of citrated whole blood using a microfluidic herringbone mixer. Biomicrofluidics,   6: 064106. PDF

Evaluation of surfactant performance in fracturing fluids for enhanced well productivity in the unconventional reservoirs using rock-on-a-chip approach. Petroleum Science and Engineering,   136: 531-541.

Physiochemical artifacts in FeCl3 thrombosis models. Blood,   126: 700-701. PDF

A vascular injury model using focal heat-induced activation of endothelial cells. Integrative Biology,   15: 801-814. PDF

Microfluidic technology as an emerging clinical tool to evaluate thrombosis and hemostasis. Thrombosis Research,   136: 13-19. PDF

Imaging of a linear diode bar for an optical cell stretcher. Biomedical Optics Express,   6: 807-814. PDF

Down in a hole: A new laser ablation model of hemostasis. Journal of Thrombosis and Haemostasis,   13: 414-416. PDF

Fluid mechanics of blood clot formation Annual Review of Fluid Mechanics,   47: 377-403. PDF

Elastic behavior and platelet retraction in low and high density fibrin gels. Biophysical Journal,   108: 173-183. PDF

Optic imaging of two-phase flow behavior in one-dimensional nano-scale channels. SPE Journal,   19 : 793-802.

A combined microfluidic-microstencil method for patterning molecules and cells. Biomicrofluidics,   8: 056502.

Platelet bioreactor-on-a-chip. Blood,   124: 1857-1867.

The effect of pore geometry and interfacial tension on water-oil displacement efficiency in oil-wet microfluidic porous media analogs. Physics of Fluids,   26: 093102.

The relative role of soluble guanylyl cylase dependent and independent pathways in nitric oxide inhibition of platelet aggregation under flow. Cellular and Molecular Bioengineering,   7: 421-431.

In vitro cell culture model for toxic inhaled chemical testing. Journal of Visualized Experiments,   87: e51539.

Thrombin generation and fibrin formation under flow on biomimetic tissue factor rich surfaces. Journal of Thrombosis and Haemostasis,   12: 372-382.

Flow-dependent thrombin and fibrin generation: Opportunities for standardization. Journal of Thrombosis and Haemostasis,   12 (2014): 418-420

Collagen-induced thrombosis in large vessels using native prothrombotic substrates Thrombosis Research,   131 (2013), 1-2. PDF

Tissue factor signals airway epithelial basal cell survival via coagulation and PAR1/2. American Journal of Respiratory Cell and Molecular Biology,   48 (2013): 94-104. PDF

High content analysis of shear dependent platelet function in a microfluidic flow assay. Annals of Biomedical Engineering,   14 (2013): 250-262 PDF

Sources of variability in platelet accumulation on type I fibrillar collagen in microfluidic flow assays. PLoS One,   8 (2013): e54680 PDF

Optic imaging of single and two-phase pressure driven flow in nano-scale channels. Lab on a Chip,   13 (2013): 1165-1171

Measuring cell mechanics by optical alignment compression cytometry Lab on a Chip,   13 (2013): 1571-1577 PDF

The hydraulic permeability of blood clots as a function of fibrin and platelet density. Biophysical Journal,   104 (2013): 1812-1823 PDF

The use of microfluidics in hemostasis: Clinical diagnostics and biomimetic models of vascular injury. Current Opinion in Hematology,   20 (2013):417-423. PDF

An inquiry-based investigation of controlled release drug delivery from hydrogels: An experiment for high school chemistry and biology. Journal of Chemical Education,   90 (2013): 918-921. PDF

Transport limitations of nitric oxide inhibition of platelet aggregation under flow. Annals of Biomedical Engineering,   41 (2013): 2193-2205. PDF

The effect of factor VIII deficiencies and replacement and bypass therapies on thrombus formation under venous flow conditions in microfluidic and computational models. PLoS One,   8 (2013): e78732 PDF

Single- and two-phase flow in microfluidic porous media analogs based on Voronoi tessellation. Lab on a Chip,   12 (2012), 253-261.

Interaction and localization of synthetic nanoparticles in healthy and cystic fibrosis airway epithelial cells: Effect of ozone exposure. Journal of Aerosol Medicine and Pulmonary Drug Delivery,   25(2012), 7-15. PDF

Real-time imaging of perivascular transport of nanoparticles during convection enhanced delivery in the rat cortex. Annals of Biomedical Engineering,   40 (2012), 292-303. PDF

Catch me if you can: Isolating circulating tumor cells from flowing blood. Clinical Chemistry,   58 (2012), 803-804. PDF

Effect of viscoelasticity on the analysis of single molecule force spectroscopy on live cells. Biophysical Journal,   103 (2012), 137-145. PDF

Characterization of collagen thin films for von Willebrand factor binding and platelet adhesion. Langmuir,   27 (2011), 13648-13658. PDF

Thrombin flux and wall shear rate regulate fibrin fiber deposition state during polymerization under flow. Biophysical Journal,   98 (2010), 1344-1352. PDF

Microfluidic probes in the treatment of brain-related diseases. Drug News and Perspectives,   23 (2010), 491-497.

DOI:

Diminished contact-dependent reinforcement of Syk activation underlies impaired thrombus growth in mice lacking Semaphorin 4D. Blood,   116 (2010), 5707-5715. PDF

Flexible microfluidic devices supported by biodegradable insertion scaffolds for convection-enhanced neural drug delivery. Biomedical Microdevices,   11 (2009), 915-924. PDF

Disruption of SEMA4D ameliorates platelet hypersensitivity in dyslipidemia and confers protection against the development of atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology,   29 (2009), 1039-1045. PDF

Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role. Proceedings of the National Academy of Sciences of the USA,   106 (2009), 21167-21172. PDF

Determination of surface tissue factor thresholds that trigger coagulation at venous and arterial shear rates: amplification of 100 fM circulating tissue factor requires flow. Blood,   111 (2008), 3507-3513. PDF

A membrane-based microfluidic device for controlling the flux of platelet agonists into flowing blood. Lab on a Chip,   8 (2008), 701-709.

Microfluidic focal thrombosis model for measuring murine platelet deposition and stability: PAR4 signaling enhances shear-resistance of platelet aggregates. Journal of Thrombosis and Haemostasis,   6 (2008), 2193-2201. PDF

Flexible multielectrodes can resolve multiple muscles in an insect appendage. Journal of Neuroscience Methods,   159 (2007), 116-124. PDF

Dilation and degradation of the brain extracellular matrix enhances penetration of infused polymer nanoparticles. Brain Research,   1180 (2007), 121-132. PDF

Fabrication and characterization of microfluidic probes for convection enhanced drug delivery. Controlled Release,   111 (2006), 252-262. PDF

Model neural prostheses with integrated microfluidics: A potential Intervention strategy for controlling reactive cell and tissue responses. IEEE Transactions on Biomedical Engineering,   51 (2004), 2063-2073. PDF